产品简介

β-半乳糖苷酶染色试剂盒(β-Galactosidase Staining Kit)是一种基于衰老时SA-β-Gal (senescence-associated β-galactosidase)活性水平上调而对衰老细胞或组织进行染色检测的试剂盒。 β-半乳糖苷酶染色试剂盒

      β-半乳糖苷酶染色试剂盒(β-Galactosidase Staining Kit)是一种基于衰老时SA-β-Gal (senescence-associated β-galactosidase)活性水平上调而对衰老细胞或组织进行染色检测的试剂盒。在普通的光学显微镜下就可以观测到细胞或组织的衰老情况。本试剂盒可以用于培养细胞的衰老检测，也可以用于组织切片的衰老检测。β-半乳糖苷酶染色试剂盒以X-Gal为底物，在衰老特异性的β-半乳糖苷酶催化下会生成深蓝色产物，光学显微镜下很容易观察到变成蓝色的表达β-半乳糖苷酶的细胞或组织。本试剂盒仅染色衰老细胞，对衰老前的细胞(presenescent cells)、静止期细胞(quiescent cells)、永生细胞(immortal cells)或肿瘤细胞等不会染色。对于组织切片或组织块，可以检测的样品数量视样品的大小而定，对于普通的切片也至少足够检测100个样品，使用6孔板测定，足够测定100个样品。 

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标题:Multi-omics analysis of human mesenchymal stem cells shows cell aging that alters immunomodulatory activity through the downregulation of PD-L1

成员:Gao Yuchen, Chi Ying, Chen Yunfei, Wang Wentian, Li Huiyuan, Zheng Wenting, Zhu Ping, An Jinying, Duan Yanan, Sun Ting, Liu Xiaofan, Xue Feng, Liu Wei, Fu Rongfeng, Han Zhibo, Zhang Yingchi, Yang Renchi, Cheng Tao, Wei Jun, Zhang Lei, Zhang Xiaomin

论文因子:16.6 发表期刊:Nature Communications pmid:37474525

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标题:A Biomimetic Peptide Functions as Specific Extracellular Matrix for Quiescence of Stem Cells against Intervertebral Disc Degeneration

成员:Yuan Li, Kuo Zhang, Xuezheng Ai, Qingshi Zhang, Lu Jiang, Jiang Long, Huange Xu, Chencheng Feng, Yaqing Zhang, Guoke Tang, Fanli Chong, Lei Wang, Bo Huang

论文因子:13.3 发表期刊:Small pmid:37423970

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标题:Peficitinib ameliorates doxorubicin-induced cardiotoxicity by suppressing cellular senescence and enhances its antitumor activity

成员:Hui Hua, Qi Zhao, Jing Xia, Qian-long Dai, Shi-rui Bai, Xiao-bo Wang, Min Zhou

论文因子:5.6 发表期刊:INTERNATIONAL IMMUNOPHARMACOLOGY pmid:37451017

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标题:Extracellular vesicles derived from HuMSCs alleviate daunorubicin-induced cardiac microvascular injury via miR-186-5p/PARP9/STAT1 signal pathway

成员:Shule Zhang, Dong Li, Linghong Liu, Qing Shi, Xiuli Ju

论文因子:4.3 发表期刊:Regenerative Therapy pmid:38327716

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标题:The CDK4/6 Inhibitor Palbociclib Induces Cell Senescence of High-grade Serous Ovarian Cancer Through Acetylation of p53

成员:Ye Cong, Cheng Yan, Qian Xiaohong, Zhong Bo, Ma Jinchun, Guo Hongling

论文因子:2.4 发表期刊:BIOCHEMICAL GENETICS pmid:38388849

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β-半乳糖苷酶染色试剂盒

β-半乳糖苷酶染色试剂盒